Complement Factor D / DyLight 350 / I8/1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-05121UV (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Complement Factor D
Clone I8/1
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 350
Target Species Human
Applications WB, ELISA
Description Clone I8/1 is specific for complement factor D in human serum and plasma
About Complement Factor D and DyLight 350
Complement Factor D This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra