Cyclin A1 / DyLight 680 / XLA1-1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-2624FR (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Cyclin A1
Clone XLA1-1
Host Mouse
Isotype IgG1
Conjugate DyLight 680
Target Species Xenopus
Applications WB
Description Mouse Cyclin A1 antibody reacts with Xenopus [DyLight 680]
About Cyclin A1 and DyLight 680
Cyclin A1 The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra