CD14 / PE-Dazzle 594 / M5E2
CD14 / PE-Dazzle 594 / M5E2
Citations:
(5)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 301852 (View supplier product page) | |
| Size | 100T | |
| Price | $347.00 | |
| Antigen | CD14 | |
| Clone | M5E2 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | PE-Dazzle 594 | |
| Target Species | Cynomolgus macaque, Human, Rhesus macaque | |
| Applications | FC | |
| Description | PE/Dazzle 594 anti-human CD14 |
About CD14 and PE-Dazzle 594
| CD14 | The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| PE-Dazzle 594 | PE-Dazzle® 594 (RPE-Dazzle 594) from Biolegend is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Dazzle 594. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Dazzle 594, which emitts light that can be captured with a 610/20 nm bandpass filter. PE-Dazzle 594 has an excitation peak at 565 nm and an emission peak at 610 nm, and is suitable alternative to PE-Texas Red, PE-eF610, PE-Alexa Fluor™ 610 or PE-CF®594. |
Images
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Human peripheral blood monocytes were stained with CD14 (clone M5E2) PE/Dazzle™ 594 (filled histogram) or mouse IgG2a, κ PE/Dazzle™ 594 isotype control (open histogram). |
Citations
| PMID 17641010 | ||
|---|---|---|
| PMID 20844193 | ||
| PMID 22942426 | ||
| Additional Sources |
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Reviews & Ratings
PE-Dazzle 594 Excitation and Emission Spectra
$347.00
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