CD8a / PE-Dazzle 594 / HIT8a
CD8a / PE-Dazzle 594 / HIT8a
Citations:
(2)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 300930 (View supplier product page) | |
| Size | 100T | |
| Price | $314.00 | |
| Antigen | CD8a | |
| Clone | HIT8a | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | PE-Dazzle 594 | |
| Target Species | Human | |
| Applications | FC | |
| Description | PE/Dazzle 594 anti-human CD8a |
About CD8a and PE-Dazzle 594
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
|---|---|---|
| PE-Dazzle 594 | PE-Dazzle® 594 (RPE-Dazzle 594) from Biolegend is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Dazzle 594. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Dazzle 594, which emitts light that can be captured with a 610/20 nm bandpass filter. PE-Dazzle 594 has an excitation peak at 565 nm and an emission peak at 610 nm, and is suitable alternative to PE-Texas Red, PE-eF610, PE-Alexa Fluor™ 610 or PE-CF®594. |
Images
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Human peripheral blood lymphocytes stained with HIT8a (clone HIT8a) PE/Dazzle™ 594 (filled histogram) or mouse IgG1, κ PE/Dazzle™ 594 isotype control (open histogram). |
Citations
| PMID 21813597 | ||
|---|---|---|
| Additional Sources |
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Reviews & Ratings
PE-Dazzle 594 Excitation and Emission Spectra
$314.00
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