CCR6 / Brilliant Violet 711 / G034E3

Citations: (12)
Product Details
Supplier BioLegend
Catalog #: 353436 (View supplier product page)
Size 100T
Price $435.00
Antigen CCR6
Clone G034E3
Host Mouse
Isotype IgG2b κ
Conjugate Brilliant Violet 711
Target Species Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description Brilliant Violet 711 anti-human CD196 (CCR6)
About CCR6 and Brilliant Violet 711
CCR6 This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Brilliant Violet 711 Brilliant™ Violet 711 (BV711) is a red-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 710/50 bandpass filter. BV711 has an excitation peak at 405 nm and an emission peak at 711 nm. BV711 exhibits a medium level of brightness and is most often used in flow cytometry, specifically, it is an alternative to nanocrystals used for intracellular flow. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.
Images
  CCR6 Brilliant Violet 711 BioLegend antibody anti target:Cynomolgus macaque, Human, Rhesus macaque host:Mouse isotype:IgG2b κ clone:G034E3

Human peripheral blood lymphocytes were stained with CD19 Alexa Fluor® 488 and CD196 (clone G034E3) Brilliant Violet 711™ (top) or mouse IgG2b, κ Brilliant Violet 711™ isotype control (bottom).

  CCR6 Brilliant Violet 711 BioLegend antibody anti target:Cynomolgus macaque, Human, Rhesus macaque host:Mouse isotype:IgG2b κ clone:G034E3

Citations
Additional
Sources
Reviews & Ratings
Brilliant Violet 711 Excitation and Emission Spectra