FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-108-131 (View supplier product page)
	Size	30 tests in 300 µL
	Price	$155.00
	Antigen	IL-22
	Clone	REA466
	Host	Human
	Isotype	IgG1
	Conjugate	Vio 515
	Target Species	Human
	Applications	FC
	Description	Clone REA466 recognizes the human interleukin-22 (IL-22) antigen, a secreted molecule which belongs to the IL-10 family of cytokines. IL-22 is produced by immune cells, including T helper cell subsets and innate lymphocytes, but acts only on non-hematopoietic stromal cells, in particular epithelial cells, keratinocytes, and hepatocytes. It plays an important role in host defense at mucosal surfaces as well as in tissue repair. Although IL-22 is beneficial to the host in many infectious and inflammatory disorders, depending on the target tissue it can be pathogenic due to its inherent pro-inflammatory properties, which are further enhanced when IL-22 is released together with other pro-inflammatory cytokines, in particular IL-17. \| Additional information: Clone REA466 displays negligible binding to Fc receptors.

	IL-22	This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. [provided by RefSeq, Jul 2018]
	Vio 515	Vio® 515 from Miltenyi has an excitation peak at 488 nm and an emission peak at 514. It is spectrally comparable to FITC, Alexa Fluor™ 488, CF®488A and DyLight™ 488.

$155.00
Supplier Page

IL-22 Monoclonal / Vio 515 / REA466