CLEC5A Monoclonal / Biotin / REA582
CLEC5A Monoclonal / Biotin / REA582
Citations:
(3)
Product Details
Supplier | Miltenyi Biotec | |
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Catalog #: | 130-110-000 (View supplier product page) | |
Size | 9 μg in 30 μl | |
Price | $35.00 | |
Antigen | CLEC5A | |
Clone | REA582 | |
Host | Human | |
Isotype | IgG1 | |
Conjugate | Biotin | |
Target Species | Mouse | |
Applications | FC | |
Description | Clone REA582 recognizes the mouse myeloid DAP12-associating lectin 1 (MDL-1) antigen, also known as C-type lectin domain family 5 member A (CLEC5A) or C-type lectin superfamily member 5 (CLECSF5). MDL-1 is type II transmembrane protein which contains a charged residue in the transmembrane region that enables it to pair with DAP12. MDL-1 is expressed on myeloid cells. It has been suggested, that MDL-1 plays an important role in immune defense as a result of an innate immunity. | Additional information: Clone REA582 displays negligible binding to Fc receptors. |
About CLEC5A and Biotin
CLEC5A | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined. [provided by RefSeq, Jul 2008] |
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Citations
PMID 10449773 | ||
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PMID 19074552 | ||
PMID 19251634 | ||
Additional Sources |
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Reviews & Ratings
Biotin Excitation and Emission Spectra
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