S100B Monoclonal / DyLight 594 / 15F9NB

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-45267DL594 (View supplier product page)
Size 0.1 ml
Price $431.00
Antigen S100B
Clone 15F9NB
Host Mouse
Isotype IgG2b κ
Conjugate DyLight 594
Target Species Human
Applications WB, FC, IHC-P, ICC/IF, IHC
About S100B and DyLight 594
S100B The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
DyLight 594 DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 594 Excitation and Emission Spectra