Pappalysin-1 / Alexa Fluor 700 / 18A10

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-73059AF700 (View supplier product page)
Size 200 μl
Price $399.00
Antigen Pappalysin-1
Clone 18A10
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 700
Target Species Human
Applications WB
About Pappalysin-1 and Alexa Fluor 700
Pappalysin-1 This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra