Pappalysin-1 / DyLight 755 / 100
Pappalysin-1 / DyLight 755 / 100
Product Details
| Supplier | Novus Biologicals, a Bio-Techne brand | |
|---|---|---|
| Catalog #: | NB120-8346IR (View supplier product page) | |
| Size | 0.2 ml | |
| Price | $469.00 | |
| Antigen | Pappalysin-1 | |
| Clone | 100 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | DyLight 755 | |
| Target Species | Human | |
| Applications | WB, ELISA | |
| Description | Human PAPP-A antigen |
About Pappalysin-1 and DyLight 755
| Pappalysin-1 | This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| DyLight 755 | DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy. |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
DyLight 755 Excitation and Emission Spectra
$469.00
Supplier Page
Supplier Page
