CD45RB / FITC / PTPRC/1147

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-47959F (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen CD45RB
Clone PTPRC/1147
Host Mouse
Isotype IgG1 κ
Conjugate FITC
Target Species Human
Applications FC, IHC-P, IHC
Description CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
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FITC Excitation and Emission Spectra