CD45RB / Alexa Fluor 700 / PTPRC/1132

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-47958AF700 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen CD45RB
Clone PTPRC/1132
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 700
Target Species Human, Monkey (Negative), Rat (Negative)
Applications WB, FC, IHC-P, IHC
Description CD45R, also designated CD45 and PTPRC, is identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
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Alexa Fluor 700 Excitation and Emission Spectra