IgG RealYellow 775 (G18-145, Mouse) - Reactivity: Human

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Description

IgG is an important component of the humoral immune response, helping to control infection.  IgG is produced by plasma B-cells and may be found in extracellular fluids, such as blood, lymph, peritoneal, and cerebrospinal fluids.  IgG monomers consist of two light and two heavy chains containing two antigen binding sites.  There are four IgG subclasses found in human, mouse and rat species, which include IgG1, IgG2, IgG3 and IgG4.  The G18-145 monoclonal antibody specifically binds to the heavy chain of human immunoglobulin G subclasses: IgG1, IgG2, IgG3 and IgG4.  The G18-145 antibody has been reported not to react with the heavy chains of other human immunoglobulin isotypes.

Conjugate RealYellow 775
Clone G18-145
Target Species Human
Applications FC
Supplier BD Biosciences
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About IgG
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]
About RealYellow 775
RealYellow™ 775 (RY775) from BD Biosciences is an alternative to PE-Cy7, PE-Vio 770 (Miltenyi) and PE-eFluor 780 (ThermoFisher) tandem fluorophores and has the advantage of discrete excitation off of the 561 nm laser without much cross-beam excitation by the 488nm laser. This limited cross-beam excitation will translate to lower complexity index scores and lower spillover spreading error in high parameter spectral flow cytometry applications.
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$192.00