CD86 Alexa Fluor 700 (C86/1146, Mouse) - Reactivity: Human, Mouse, Rat

Product Details
Description B7-2/CD86 Antibody (C86/1146) [Alexa Fluor® 700]
Conjugate Alexa Fluor 700
Clone C86/1146
Target Species Human, Mouse, Rat
Applications ICC, WB, FC, IHC, IF, IHC-P, CyTOF, Knockout Validated
Supplier Novus Biologicals, a Bio-Techne brand
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About CD86
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
About Alexa Fluor 700
Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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$549.00