CD11b Alexa Fluor Plus 594 (C67F154, Mouse) - Reactivity: Human
Product Details
| Description | CD11b | |
|---|---|---|
| Conjugate | Alexa Fluor Plus 594 | |
| Clone | C67F154 | |
| Target Species | Human | |
| Applications | IHC | |
| Supplier | Thermo Fisher Scientific | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About Alexa Fluor Plus 594
Alexa Fluor™ Plus 594 is a fluorescent dye with an excitation peak at 590 nm and an emission peak at 618 nm. The Alexa Fluor ™ Plus line of reagents have increased brightness and photostability to enable researchers to detect and visualize low-abundance targets in rare or precious samples.
Alexa Fluor™ Plus 594 is a fluorescent dye with an excitation peak at 590 nm and an emission peak at 618 nm. The Alexa Fluor ™ Plus line of reagents have increased brightness and photostability to enable researchers to detect and visualize low-abundance targets in rare or precious samples.
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