Antibody Search
OMIPs
eLearning 
Dye Directory
CD86 PE-Fire 700 (IT2.2, Mouse) - Reactivity: Cynomolgus macaque, Human, Rhesus macaque
Product Details
| Description | PE/Fire 700 anti-human CD86 | |
|---|---|---|
| Conjugate | PE-Fire 700 | |
| Clone | IT2.2 | |
| Target Species | Cynomolgus macaque, Human, Rhesus macaque | |
| Applications | FC | |
| Supplier | Sony | |
| Catalog # | Sign in to view product details, citations, and spectra | |
| Size | ||
| Price | ||
| Antigen | ||
| Host | ||
| Isotype |
About CD86
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
About PE-Fire 700
PE-Fire™ 700 from Biolegend is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Fire™ 700. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Fire™ 700. This tandem has an excitation peak at 565 nm and an emission peak at 695 nm.
PE-Fire™ 700 from Biolegend is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Fire™ 700. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Fire™ 700. This tandem has an excitation peak at 565 nm and an emission peak at 695 nm.
Experiment Design Tools
Spectra Viewer
Validation References
| Additional Sources |
|
|---|
Reviews & Ratings
| Reviews |
|---|
