EphB2 / PE / 001

Product Details
Supplier Sino Biological
Catalog #: 10762-R001-P (View supplier product page)
Size 100 Tests
Price $90.00
Antigen EphB2
Clone 001
Host Rabbit
Isotype IgG
Conjugate PE
Target Species Human
Applications FC
Description This antibody was obtained from a rabbit immunized with purified, recombinant Human EPHB2 / Hek5 (rh EPHB2 / Hek5; Catalog#10762-H08H; NP_059145.2; Met1-Leu543) and conjugated with PE under optimum conditions, the unreacted PE was removed.
About EphB2 and PE
EphB2 This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

PE Excitation and Emission Spectra