IRF-6 / PE / 14B2C16

Product Details
Supplier BioLegend
Catalog #: 674504 (View supplier product page)
Size 100 Tests
Price $358.00
Antigen IRF-6
Clone 14B2C16
Host Mouse
Isotype IgG2a κ
Conjugate PE
Target Species Human
Applications ICS
Description PE anti-IRF6
About IRF-6 and PE
IRF-6 This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Images
  IRF-6 PE BioLegend antibody anti target:Human host:Mouse isotype:IgG2a κ clone:14B2C16

HaCat cells were treated with Fixation Buffer and permeabilized with True-Phos™ Perm Buffer, then stained with anti-IRF6 (clone 14B2C16) PE (filled histogram) or mouse IgG2a, κ PE (open histogram).

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PE Excitation and Emission Spectra