CD49f / APC-Cy7 / GoH3

Citations: (1)
Product Details
Supplier BioLegend
Catalog #: 313627 (View supplier product page)
Size 25T
Price $176.00
Antigen CD49f
Clone GoH3
Host Rat
Isotype IgG2a κ
Conjugate APC-Cy7
Target Species Cynomolgus macaque, Human, Mouse, Rhesus macaque
Applications FC
Description APC/Cyanine7 anti-human/mouse CD49f
About CD49f and APC-Cy7
CD49f The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
APC-Cy7 APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare.
Images
  CD49f APC-Cy7 BioLegend antibody anti target:Cynomolgus macaque, Human, Mouse, Rhesus macaque host:Rat isotype:IgG2a κ clone:GoH3

Human peripheral blood lymphocytes were stained with CD49f (clone GoH3) APC/Cyanine7 (filled histogram) or Rat IgG2a, κ APC/Cyanine7 isotype control (open histogram).

Citations
Reviews & Ratings
APC-Cy7 Excitation and Emission Spectra