PD-1 / APC-Fire 750 / EH12.2H7
PD-1 / APC-Fire 750 / EH12.2H7
Citations:
(2)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 329953 (View supplier product page) | |
| Size | 25T | |
| Price | $176.00 | |
| Antigen | PD-1 | |
| Clone | EH12.2H7 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | APC-Fire 750 | |
| Target Species | Human | |
| Applications | FC | |
| Description | APC/Fire 750 anti-human CD279 (PD-1) |
About PD-1 and APC-Fire 750
| PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| APC-Fire 750 | APC-Fire™ 750 from Biolegend has an excitation peak at 651 nm and an emission peak at 788 nm and is most commonly used in flow cytometry. Spectrally its similar to APC-Cy7, APC-Alexa 750 and APC-H7 |
Images
|
PHA-stimulated (day 3) human peripheral blood lymphocytes were stained with CD279 (clone EH12.2H7) APC/Fire™ 750 (filled histogram) or mouse IgG1, κ APC/Fire™ 750 isotype control (open histogram). |
Citations
| PMID 18829748 | ||
|---|---|---|
| PMID 18981087 | ||
| PMID 19553327 | ||
| PMID 19889785 | ||
| PMID 20100932 | ||
| PMID 21398606 | ||
| PMID 21562156 | ||
| Additional Sources |
|
Reviews & Ratings
APC-Fire 750 Excitation and Emission Spectra
$176.00
Supplier Page
Supplier Page
