SUN2 / Unconjugated /
SUN2 / Unconjugated /
Product Details
| Supplier | Creative Diagnostics | |
|---|---|---|
| Catalog #: | DMAB9325 (View supplier product page) | |
| Size | Inqμire | |
| Price | ||
| Antigen | SUN2 | |
| Clone | ||
| Host | Mouse | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | C. elegans | |
| Applications | ||
| Description | Anti-C. elegans Monoclonal antibody |
About SUN2 and Purified
| SUN2 | SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010] |
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Citations
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