Bcl-6 / Unconjugated / FQS22521-54
Bcl-6 / Unconjugated / FQS22521-54
Product Details
| Supplier | Creative Diagnostics | |
|---|---|---|
| Catalog #: | DCABH-5769 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | Bcl-6 | |
| Clone | FQS22521-54 | |
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse, Rat | |
| Applications | ||
| Description | Anti-BCL6 monoclonal antibody, clone FQS22521-54 |
About Bcl-6 and Purified
| Bcl-6 | The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
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Citations
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