FluoroFinder

	Supplier	Beckman Coulter
	Catalog #:	B49195 (View supplier product page)
	Size	0.5 mL
	Price
	Antigen	CD43
	Clone	DFT1
	Host	Mouse
	Isotype	IgG1
	Conjugate	APC-Alexa 750
	Target Species	Human
	Applications	Cell Labeling, Blind Panel, Allergenicity, Platelets
	Description	CD43-APC-A750, DFT1, 50 Tests, CE

	CD43	This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
	APC-Alexa 750	APC-Alexa 750 from Thermo Fisher Scientific has an excitation peak at 651 nm and an emission peak at 775 nm and is most commonly used in flow cytometry.

	Additional Sources

CD43 / APC-Alexa 750 / DFT1