Sur-2 / Unconjugated / D27-1805

Citations: (18)
Product Details
Supplier BD Biosciences
Catalog #: 550429 (View supplier product page)
Size 100 μg
Price $368.00
Antigen Sur-2
Clone D27-1805
Host Mouse
Isotype IgG1 κ
Conjugate Unconjugated
Target Species Human
Applications WB
Description Hu Sur-2 Pure D27-1805 100ug
About Sur-2 and Purified
Sur-2 The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]
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Purified Excitation and Emission Spectra