OCT-3/4 / PerCP-Cy5.5 / O50-808
OCT-3/4 / PerCP-Cy5.5 / O50-808
Product Details
| Supplier | BD Biosciences | |
|---|---|---|
| Catalog #: | 562251 (View supplier product page) | |
| Size | 50 Tests | |
| Price | ||
| Antigen | OCT-3/4 | |
| Clone | O50-808 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | PerCP-Cy5.5 | |
| Target Species | Human, Mouse | |
| Applications | FC | |
| Description | OCT3/4A PerCP-Cy5.5 O50-808 50Tst |
About OCT-3/4 and PerCP-Cy5.5
| OCT-3/4 | This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013] | |
|---|---|---|
| PerCP-Cy5.5 | PerCP-Cyanine® 5.5 (PerCP-Cy5.5) is a red-emitting tandem fluorophore that was originally designed to make the PerCP fluorophore more stable and increase signal intensity. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, Cy5.5, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-Cy5.5 has an excitation peak at 482 nm and an emission peak at 695 nm. There are superior alternatives to PerCP and PerCP-Cy5.5 including RealBlue 705 (BD Biosciences), NovaFluor Blue 690 or PerCP-eFluor™ 710. |
Citations
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