FluoroFinder

	Supplier	Biotium
	Catalog #:	BNC741050-100 (View supplier product page)
	Size	100 μl
	Price	$205.00
	Antigen	CD3e
	Clone	CRIS-7
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	CF740
	Target Species	Human, Monkey
	Applications	Functional, FC, FC, IF
	Description	Recognizes the epsilon chain of CD3 (Workshop V; Code: CD03.09), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

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$205.00
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CD3e / CF740 / CRIS-7