ULBP-2 / Unconjugated / E9G2P

Product Details
Supplier Cell Signaling Technology
Catalog #: 52827S (View supplier product page)
Size 100 μl
Price $339.00
Antigen ULBP-2
Clone E9G2P
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB
Description ULBP2 (E9G2P) Rabbit mAb recognizes endogenous levels of total ULBP2 protein. This antibody cross-reacts weakly with human ULBP4 and ULBP5 proteins.
About ULBP-2 and Purified
ULBP-2 This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra