SMAD3 / Alexa Fluor 488 / C67H9

Product Details
Supplier Cell Signaling Technology
Catalog #: 31626S (View supplier product page)
Size 100 μl
Price $450.00
Antigen SMAD3
Clone C67H9
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 488
Target Species Human, Monkey, Mouse, Rat
Applications FC
Description SMAD3 (C67H9) Rabbit mAb (Alexa Fluorsup>/sup> 488 Conjugate) detects endogenous levels of total SMAD3 protein. No cross-reactivity was detected with other family members.
About SMAD3 and Alexa Fluor 488
SMAD3 The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. It also functions as a tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, Nov 2019]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra