PHF8 / Unconjugated / E6K3Y

Product Details
Supplier Cell Signaling Technology
Catalog #: 93801T (View supplier product page)
Size 20 μl
Price $153.00
Antigen PHF8
Clone E6K3Y
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Monkey, Mouse, Rat
Applications WB, IP, ChIP, ChIP-seq
Description PHF8 (E6K3Y) Rabbit mAb recognizes endogenous levels of total PHF8 protein.
About PHF8 and Purified
PHF8 The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
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Purified Excitation and Emission Spectra