PHF8 / Unconjugated / E9R4F

Product Details
Supplier Cell Signaling Technology
Catalog #: 37377T (View supplier product page)
Size 20 μl
Price $153.00
Antigen PHF8
Clone E9R4F
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Monkey
Applications WB, IP, FC, ChIP
Description PHF8 (E9R4F) Rabbit mAb recognizes endogenous levels of total PHF8 protein.
About PHF8 and Purified
PHF8 The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
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Purified Excitation and Emission Spectra