ITCH / Unconjugated / 32/Itch

Citations: (18)
Product Details
Supplier BD Biosciences
Catalog #: 611199 (View supplier product page)
Size 150 μg
Price $546.00
Antigen ITCH
Clone 32/Itch
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human, Mouse, Rabbit, Rat
Applications WB, IF
Description Itch Pure 32/Itch 150ug
About ITCH and Purified
ITCH This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
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Purified Excitation and Emission Spectra