CD8a MultiDot 610 (SK1, Mouse) - Reactivity: Human

About CD8a
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]

About MultiDot 610
MultiDot 610 is an orange emitting fluorophore optimally excited from 320 nm to 405 nm with an emission peak at 610 nm. This dye is part of Core Quantum Technologies' MultiDot product line. Each MultiDot consists of several quantum dots with a patented coating, resulting in increased sensitivity and a tighter emission spectrum which limits spectral overlap.