Perforin / APC-Fire 750 / S16009A
Perforin / APC-Fire 750 / S16009A
Product Details
| Supplier | Sony | |
|---|---|---|
| Catalog #: | 1371590 (View supplier product page) | |
| Size | 100 μg | |
| Price | $430.00 | |
| Antigen | Perforin | |
| Clone | S16009A | |
| Host | Rat | |
| Isotype | IgG2a κ | |
| Conjugate | APC-Fire 750 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | APC/Fire 750 anti-mouse Perforin |
About Perforin and APC-Fire 750
| Perforin | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| APC-Fire 750 | APC-Fire™ 750 from Biolegend has an excitation peak at 651 nm and an emission peak at 788 nm and is most commonly used in flow cytometry. Spectrally its similar to APC-Cy7, APC-Alexa 750 and APC-H7 |
Citations
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