CD27 / Spark UV 387 / O323
CD27 / Spark UV 387 / O323
Product Details
Supplier | Sony | |
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Catalog #: | 2114325 (View supplier product page) | |
Size | 25 Tests | |
Price | $128.00 | |
Antigen | CD27 | |
Clone | O323 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | Spark UV 387 | |
Target Species | African Green Monkey, Baboon, Cynomolgus macaque, Human, Rhesus macaque, Squirrel Monkey | |
Applications | FC | |
Description | Spark UV 387 anti-human CD27 |
About CD27 and Spark UV 387
CD27 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] | |
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Spark UV 387 | Spark UV® 387 from Biolegend is a fluorophore with an excitation peak at 351 nm and an emission peak at 387 nm. This fluorophore is an alternative to Alexa Fluor™ 350 and can be excited by the 355 nm laser. |