CD27 / Spark UV 387 / O323

Product Details
Supplier Sony
Catalog #: 2114325 (View supplier product page)
Size 25 Tests
Price $128.00
Antigen CD27
Clone O323
Host Mouse
Isotype IgG1 κ
Conjugate Spark UV 387
Target Species African Green Monkey, Baboon, Cynomolgus macaque, Human, Rhesus macaque, Squirrel Monkey
Applications FC
Description Spark UV 387 anti-human CD27
About CD27 and Spark UV 387
CD27 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Spark UV 387 Spark UV® 387 from Biolegend is a fluorophore with an excitation peak at 351 nm and an emission peak at 387 nm. This fluorophore is an alternative to Alexa Fluor™ 350 and can be excited by the 355 nm laser.
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Spark UV 387 Excitation and Emission Spectra