CD27 / Spark Violet 423 / M-T271

Product Details
Supplier Sony
Catalog #: 356441 (View supplier product page)
Size 25 Tests
Price $170.00
Antigen CD27
Clone M-T271
Host Mouse
Isotype IgG1 κ
Conjugate Spark Violet 423
Target Species Human
Applications FC
Description Spark Violet 423 anti-human CD27
About CD27 and Spark Violet 423
CD27 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Spark Violet 423 Spark Violet 423 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 400 nm and an emission peak at 423 nm. This fluorophore is an alternative to BV421 and can be excited by the 405 nm laser.
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Spark Violet 423 Excitation and Emission Spectra