IFN-gamma / Vio 667 / REA1343

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-133-383 (View supplier product page)
Size 100 tests in 200 µL
Price $360.00
Antigen IFN-gamma
Clone REA1343
Host Human
Isotype IgG1
Conjugate Vio 667
Target Species Human
Applications FC
Description Clone REA1343 recognizes Interferon gamma (IFN-γ), which is produced by cells that are involved in inflammatory immune responses. IFN-γ is predominantly released by memory and effector CD4+ and CD8+ T cells as well as by NK cells upon activation. Interferon-γ (IFN-γ) plays a crucial role in activation of cellular immunity and subsequently, stimulation of antitumor immune-response. The concentration of IFN-γ plays an important role in tumor treatment, depending on the dose it can lead to tumor growth or regression. | Additional information: Clone REA1343 displays negligible binding to Fc receptors |
About IFN-gamma and Vio 667
IFN-gamma This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
Vio 667 Vio® 667 from Miltenyi has an excitation peak at 635 nm and an emission peak at 668. It is spectrally comparable to Cy5 and Alexa Fluor™ 647.
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Vio 667 Excitation and Emission Spectra