p53 Monoclonal / CoraLite 594 / 6C4B6

Product Details
Supplier Proteintech
Catalog #: CL594-60283-100UL (View supplier product page)
Size 100 μl
Price $479.00
Antigen p53
Clone 6C4B6
Host Mouse
Isotype IgG2b
Conjugate CoraLite 594
Target Species Human, Mouse, Rat
Applications ICC/IF, FC
Description The P53 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human P53. This antibody recognizes human, mouse, rat antigen. The P53 antibody has been validated for the following applications: IF/ICC, FC (Intra) analysis. This antibody is coralite®594.
About p53 and CoraLite 594
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
CoraLite 594 CoraLite 594 from Proteintech has an excitation peak at 594 nm and an emission peak at 615 nm. It is spectrally similar to Alexa Fluor™ 594, ATTO594 and DyLight™ 594 and can be useful in fluorescence microscopy.
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CoraLite 594 Excitation and Emission Spectra