p53 Polyclonal / CoraLite Plus 488 /

Product Details
Supplier Proteintech
Catalog #: CL488-10442-100UL (View supplier product page)
Size 100 μl
Price $479.00
Antigen p53
Clone
Host Rabbit
Isotype IgG
Conjugate CoraLite Plus 488
Target Species Human, Rat
Applications ICC/IF, FC
Description The P53 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human P53. This antibody recognizes human, rat antigen. The P53 antibody has been validated for the following applications: IF/ICC, FC (Intra) analysis. This antibody is coralite® plus 488.
About p53 and CoraLite Plus 488
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
CoraLite Plus 488 CoraLite Plus 488 from Proteintech has an excitation peak at 488 nm and an emission peak at 515 nm. It is spectrally similar to CF®488A and Alexa Fluor™ 488 and can be useful in fluorescence microscopy and flow cytometry.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

CoraLite Plus 488 Excitation and Emission Spectra