CREBL2 Monoclonal / Unconjugated / 3E1H8

Product Details
Supplier Proteintech
Catalog #: 68949-2-PBS-100UG (View supplier product page)
Size 100 μg
Price $699.00
Antigen CREBL2
Clone 3E1H8
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications CBA, ELISA
Description The CREBL2 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human CREBL2. This antibody recognizes human antigen. The CREBL2 antibody has been validated for the following applications: Cytometric bead array, Indirect ELISA analysis.
About CREBL2 and Purified
CREBL2 cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene. [provided by RefSeq, Jul 2008]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra