Dnmt3b Monoclonal / Unconjugated / 1F12B3

Product Details
Supplier Proteintech
Catalog #: 68919-6-PBS-100UG (View supplier product page)
Size 100 μg
Price $699.00
Antigen Dnmt3b
Clone 1F12B3
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human
Applications CBA, ELISA
Description The DNMT3B antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human DNMT3B. This antibody recognizes human antigen. The DNMT3B antibody has been validated for the following applications: Cytometric bead array, Indirect ELISA analysis.
About Dnmt3b and Purified
Dnmt3b CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
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Purified Excitation and Emission Spectra