ITCH Monoclonal / Unconjugated / 2E3G9

Product Details
Supplier Proteintech
Catalog #: 67757-1-IG-20UL (View supplier product page)
Size 20 μl
Price $149.00
Antigen ITCH
Clone 2E3G9
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, ICC/IF, IP, ELISA
Description The ITCH antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human ITCH. This antibody recognizes human, mouse, rat antigen. The ITCH antibody has been validated for the following applications: WB, IF/ICC, ELISA analysis.
About ITCH and Purified
ITCH This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
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Purified Excitation and Emission Spectra