Spastin Monoclonal / Unconjugated / 1F5A7

Product Details
Supplier Proteintech
Catalog #: 67361-1-PBS-100UG (View supplier product page)
Size 100 μg
Price $699.00
Antigen Spastin
Clone 1F5A7
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human, Mouse
Applications WB, IF, IHC, ELISA
Description The SPAST antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human SPAST. This antibody recognizes human, mouse antigen. The SPAST antibody has been validated for the following applications: WB, IHC, IF-P, Indirect ELISA analysis.
About Spastin and Purified
Spastin This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The use of alternative translational initiation sites in this gene results in a single transcript variant that can produce isoforms that differ in the length of their N-terminus and which thereby differ in the efficiency of their export from the nucleus to the cytoplasm. In addition, alternative splicing results in multiple transcript variants that encode isoforms that differ in other protein regions as well. One isoform of this gene has been shown to be a microtubule-severing enzyme that regulates microtubule abundance, mobility, and plus-end distribution. Mutations in this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq, May 2018]
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Purified Excitation and Emission Spectra