BLNK Monoclonal / Unconjugated / 1A1A1

Product Details
Supplier Proteintech
Catalog #: 66953-1-IG-20UL (View supplier product page)
Size 20 μl
Price $149.00
Antigen BLNK
Clone 1A1A1
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human, Mouse, Porcine, Rat
Applications WB, IHC, ICC/IF, ELISA
Description The BLNK antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human BLNK. This antibody recognizes human, pig, mouse, rat antigen. The BLNK antibody has been validated for the following applications: WB, IHC, IF/ICC, ELISA analysis.
About BLNK and Purified
BLNK This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
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Purified Excitation and Emission Spectra