BBS10 Monoclonal / Unconjugated / 4C6A10

Product Details
Supplier Proteintech
Catalog #: 66679-1-IG-20UL (View supplier product page)
Size 20 μl
Price $149.00
Antigen BBS10
Clone 4C6A10
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human
Applications WB, IHC, ELISA
Description The BBS10 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human BBS10. This antibody recognizes human antigen. The BBS10 antibody has been validated for the following applications: WB, IHC, ELISA analysis.
About BBS10 and Purified
BBS10 This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10. [provided by RefSeq, Jan 2010]
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Purified Excitation and Emission Spectra