CD21 / FITC / LB21

Citations: (13)
Product Details
Supplier Bio-Rad
Catalog #: MCA1195F (View supplier product page)
Size 100 μg
Price $316.00
Antigen CD21
Clone LB21
Host Mouse
Isotype IgG1
Conjugate FITC
Target Species Human
Applications FC
Description MOUSE ANTI HUMAN CD21:FITC
About CD21 and FITC
CD21 This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
FITC Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.
Images
  CD21 FITC Bio-Rad antibody anti target:Human host:Mouse isotype:IgG1 clone:LB21 Staining of human peripheral blood lymphocytes with FITC conjugated Mouse anti Human CD21 antibod...

Staining of human peripheral blood lymphocytes with FITC conjugated Mouse anti Human CD21 antibody, clone LB21 (MCA1195F)

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FITC Excitation and Emission Spectra