Bestrophin 1 Monoclonal / Unconjugated / 4D5F1

Product Details
Supplier Proteintech
Catalog #: 60326-1-PBS-100UG (View supplier product page)
Size 100 μg
Price $699.00
Antigen Bestrophin 1
Clone 4D5F1
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications WB, IF, ELISA
Description The Bestrophin-1 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human Bestrophin-1. This antibody recognizes human antigen. The Bestrophin-1 antibody has been validated for the following applications: WB, IF/ICC, Indirect ELISA analysis.
About Bestrophin 1 and Purified
Bestrophin 1 This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
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Purified Excitation and Emission Spectra