Integrin alpha 8 Polyclonal / Unconjugated /

Product Details
Supplier Proteintech
Catalog #: 55068-1-AP-20UL (View supplier product page)
Size 20 μl
Price $149.00
Antigen Integrin alpha 8
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications WB, ELISA
Description The Integrin alpha-8 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Integrin alpha-8. This antibody recognizes human, mouse antigen. The Integrin alpha-8 antibody has been validated for the following applications: WB, ELISA analysis.
About Integrin alpha 8 and Purified
Integrin alpha 8 Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2014]
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Purified Excitation and Emission Spectra