CD8a / Pacific Blue / YCATE55.9
CD8a / Pacific Blue / YCATE55.9
Citations:
(48)
Product Details
| Supplier | Bio-Rad | |
|---|---|---|
| Catalog #: | MCA1039PB (View supplier product page) | |
| Size | 100 Tests/1ml | |
| Price | $528.00 | |
| Antigen | CD8a | |
| Clone | YCATE55.9 | |
| Host | Rat | |
| Isotype | IgG1 | |
| Conjugate | Pacific Blue | |
| Target Species | Canine | |
| Applications | FC | |
| Description | RAT ANTI DOG CD8:Pacific Blue® |
About CD8a and Pacific Blue
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
|---|---|---|
| Pacific Blue | Pacific Blue® (Pac Blue, PacBlue) is a blue-emitting organic fluorophore that can be excited by the 405 nm Violet laser and captured with a 450/50 nm bandpass filter. Pacific Blue has an excititaion peak at 401 nm and an emission peak at 452 nm. |
Images
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Figure A. RPE conjugated Rat anti Dog CD4 (MCA1038PE) and Alexa Fluor 647 conjugated Rat IgG2b isotype control (MCA6006A647). Figure B. RPE conjugated Rat anti Dog CD4 (MCA1038PE) and Alexa Fluor 647 conjugated Rat anti Dog CD8 (MCA1039A647). All experiments performed on red cell lysed canine blood gated on lymphoid cells in the presence of 10% dog serum. Data acquired on the ZE5™ Cell Analyzer. |
Citations
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Reviews & Ratings
Pacific Blue Excitation and Emission Spectra
$528.00
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