PTPN13 Polyclonal / Unconjugated /

Citations: (5)
Product Details
Supplier Proteintech
Catalog #: 25944-1-AP-150UL (View supplier product page)
Size 150 μl
Price $449.00
Antigen PTPN13
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB, IHC, IF, ELISA
Description The PTPN13 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PTPN13. This antibody recognizes human antigen. The PTPN13 antibody has been validated for the following applications: WB, IHC, ELISA analysis.
About PTPN13 and Purified
PTPN13 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008]
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Purified Excitation and Emission Spectra