REST Polyclonal / Unconjugated /

Citations: (21)
Product Details
Supplier Proteintech
Catalog #: 22242-1-AP-20UL (View supplier product page)
Size 20 μl
Price $149.00
Antigen REST
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Rat
Applications WB, IHC, IF, IP, CoIP, ChIP, ELISA
Description The REST antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human REST. This antibody recognizes human, rat antigen. The REST antibody has been validated for the following applications: WB, IP, IHC, ELISA analysis.
About REST and Purified
REST This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]
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Purified Excitation and Emission Spectra